TGF-β1,human 100µg 生長(zhǎng)分化因子

產(chǎn)品英文名稱：TGF-β1,human，TGF-β1-100
產(chǎn)品中文名稱：人TGF-β1蛋白

TGF-β1產(chǎn)品介紹：
轉(zhuǎn)化生長(zhǎng)因子β(transforming growth factor)家族由一類(lèi)結(jié)構(gòu)、功能相關(guān)的多肽生長(zhǎng)因子 亞家族組成，其中包括TGF-β、活化素(activin)、骨形態(tài)發(fā)生蛋白(BMP)、生長(zhǎng)分化因子( GDF)等。TGF-β除了影響細(xì)胞的增殖、分化，還在胚胎發(fā)育、胞外基質(zhì)形成、 骨的形成和重建等方面起著重要作用。TGF-β家族成員廣泛存在于從果蠅到人多種生物的 各種組織中，對(duì)正常細(xì)胞、癌變細(xì)胞都有著顯著作用。

TGF-β1產(chǎn)品特性：
? TGF-β1活性經(jīng)過(guò)人源細(xì)胞鑒定，純度高。
? 生物活性在人源293細(xì)胞經(jīng)過(guò)SMAD實(shí)驗(yàn)鑒定The EC50為 0.1–1.0 ng/ml。
? TGF-β1產(chǎn)品經(jīng)過(guò)SDS-PAGE 和HPLC雙層鑒定純度大于95%。

TGF-β1產(chǎn)品英文簡(jiǎn)述：
Members of TGF-family are multifunctional cytokines that regulate cell proliferation, growth, differentiation and migration as well as synthesis of the extracellular matrix. The three human isoforms, TGF- 1,  2,  3, signal through the same receptor and elicit similar biological responses. The release of biologically active TGF-isoform from a latent complex involves proteolytic processing of the complex. TGF-1 is the most abundant isoform secreted by almost all cell types. Human TGF-1 is a 25.0kDa protein with each subunit containing 112 amino acid residues, linked by a disulfide bond.

? Purity: Greater than 95% as determined by SDS-PAGE and HPLC analyses
? Biological Activity: The activity was determined by using a SMAD reporter gene assay in human 293 cells. The EC50 ranges from 0.1 – 1.0 ng/ml.
? For Research Use Only. Not for Use in Humans.

重慶市華雅干細(xì)胞技術(shù)有限公司